By Barbara J. Bain
This well known notebook has been up to date and extended all through, offering a concise view of diagnostic haematology, in a handy and functional format.A Beginner's advisor to Blood Cells is a perfect for;Trainee laboratory technicians and scientists scholars learning the body structure or pathology of the blood these getting ready for haematology examinationsWhy purchase This Book?Unique pocket consultant, written via Barbara Bain – a world-renowned professional within the box of blood morphology Outlines the fundamentals of diagnostic haematology comprises a useful self-assessment part new version – now comprises additional info on medical facets and extra checks
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Additional info for A Beginner's Guide to Blood Cells, Second Edition
This process is also known as crenation. 26 Chapter 1 Fig. 20 Storage artefact. The red cells are crenated, a lymphocyte (right) has a fuzzy outline and one of the two neutrophils (left) has a nucleus which has become round, dense and homogeneous. (Compare the degenerating neutrophil with the nucleated red cells shown in Fig. ) Some of the white cells develop fuzzy outlines or disintegrate entirely when the blood ﬁlm is spread. The nuclei of neutrophils become dense, homogeneous and round and may break up into two or more round masses.
1. Polycythaemia vera Polycythaemia vera, also referred to as polycythaemia rubra vera or primary proliferative polycythaemia, is a myeloproliferative disorder characterized by overproduction of red cells. In many patients there is also overproduction of white cells and platelets. Clinical features are facial plethora and sometimes a moderate degree of splenomegaly. The disease may be complicated by arterial thrombosis and peripheral ischaemia. 1 Some important causes of polycythaemia, classiﬁed according to mechanism.
Another common cytoplasmic abnormality, which is strongly suggestive of infection, is cytoplasmic vacuolation (Fig. 4). Assessing White Cells and Platelets 47 Fig. 1 Leucocytosis. Fig. 2 Thrombocytopenia (in Wiskott–Aldrich syndrome). There are only two platelets in the ﬁlm. The platelets are also abnormally small, although their staining characteristics are normal. Fig. 3 Thrombocytosis (in chronic granulocytic leukaemia). The platelets also show increased variation in size and some are agranular.