By Shi Wei
Bone is a dwelling tissue susceptible to strengthen a various array of inflammatory, metabolic, genetic, reactive, circulatory and neoplastic abnormalities. The Atlas of Bone Pathology describes and selectively illustrates the traditional and pathologic stipulations that afflict human bone, focusing seriously on tumor and tumor-like stipulations of bone and their non-neoplastic mimics. Supplemented with radiographic and specific examine photographs, this striking selection of prime quality electronic pictures reduction carrying on with efforts to acknowledge, comprehend, and correctly interpret the sunshine microscopic findings in bone specimens.
Authored through nationally and the world over well-known pathologists, The Atlas of Bone Pathology is a concise and resource for either amateur and professional pathologists alike.
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Additional resources for Atlas of Bone Pathology
A sclerosing type of conventional osteosarcoma involving the proximal humerus shows an extensive chemotherapeutic effect. The histologic section reveals 95 % tumor necrosis 43 44 2 Bone-Forming Tumors Fig. 37 Conventional osteosarcoma. Radiograph of the corresponding specimen in Fig. 36 Fig. 38 Conventional osteosarcoma. A mixed fibroblastic and chondroblastic osteosarcoma involving the proximal humerus in a 31-yearold woman. 4 Conventional Osteosarcoma Fig. 39 Osteoblastic osteosarcoma. Even at this scanning power, abundant tumor osteoid imparting a basket-weave appearance can be visualized Fig.
A section from the lesion shown in Fig. 2 2 Bone-Forming Tumors Osteoid Osteoma Fig. 5 Osteoid osteoma. CT scan of the left tibia of a 15-year-old girl. The tumor is demonstrated as a small radiolucency (corresponding to the histologic nidus), which elicits extensive surrounding sclerosis and a cortical reaction. Commonly seen in patients in their teens and twenties, the tumor typically arises in the diaphyseal and metaphyseal regions of long tubular bones, especially the femur. Osteoid osteoma frequently originates in the cortex.
Note the prominent osteoid production reminiscent of amyloid. This, along with the plasmacytoid cytologic appearance of the tumor cells seen in the previous image, again may result in a misinterpretation of plasmacytoma or multiple myeloma Fig. 50 Conventional osteosarcoma.